Protein Details: Potassium voltage-gated channel subfamily G member 4

Protein ID

ICDB_Pro_1188

Protein Name

Potassium voltage-gated channel subfamily G member 4

Gene Name

Kcng4

Organism

Mus musculus (Mouse)

Length

506 amino acids

AlphaFoldDB

AF-Q80XM3-F1-model_v4.pdb

Function

Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1

Sequence

MPMSSRDRDLHPGHHHFGSCSPLSQLWPGPEPKSVKGLYYSRARKVGNQDASPEANLKEILVNVGGQRYLLPWSTLDAFPLSRLSRLRLCRSHEEITQLCDDYDEDSQEFFFDRNPSAFGVIVSFLAAGKLVLLREMCALSFREELSYWGIEETNLERCCLRKLLKKLEEAAELRREEAAQRQQQRQACHSEVQASRWARSMNQLREMVEDPQSGLPGKVFACLSVLFVATTAVSLCVSTMPDFRAEEGKGECTRKCYYIFVVESICVAWFSLEFCLRFVQAPNKCQFFRGPLNVIDILAISPYYVSLAVSDESPEAGERPSSSSYLEKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTVRRCAREFGLLMLFLAVAVTLFSPLVYVAENESGRVLEFTSIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELKREQEQVQARLRRLQNTNSASERELLSDVDDLVPEGLTSPGRYM

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

DOI ID

10.1101/gr.2596504

RefSeq

NP_080010.2; XP_006531352.1